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友善列印3D Cell Culture Microplates

研究指出,在臨床前期藥篩試驗顯現效果的化合物中,僅 5% 可成為合法上市的藥物 (Hutchinson et al., Nature Rev. Clin Oncol.)。傳統 2D culture 的試驗有其侷限性,採用更貼近真實癌細胞的 3D 腫瘤球 (spheroid) 試驗,更能幫助研究者快速取得貼近生理狀態的實驗數據。

美商 PerkinElmer 針對 3D 腫瘤球實驗,提供多款專用細胞培養盤商品可供選擇,包含 Ultra-low attachment (ULA) plate,具備極低貼附性表面,讓細胞易於形成腫瘤球;以及帶有獨家設計 Hanging-drop 系統的 GravityPLUS™ plate,適用於初代細胞等在 ULA plate 上難以形成腫瘤球的細胞選用。

 

Workflow of GravityPLUS™ Hanging Drop System 96–well - Microtissue formation in the GravityPLUS™ Plate and subsequent transfer to the corresponding non-adhesively coated wells of the GravityTRAP™ Plate for further cultivation and downstream applications.

 

訂購資訊

  CellCarrier
Spheroid ULA Plate
GravityTRAP™
ULA Plate
GravityPLUS™
Hanging Drop System
Plate format 96-well, transparent 96-well, transparent 96-well, transparent
Well shape U-shaped Conical shape, flat bottom Two part system: Hanging
drop plate with conical,
flat bottom capture plate
Automatable +++ +++ +++
Co-culturing + + +++
Media exchange + +++ +++
Consistency of spheroid formation ++ ++ +++
Recommended cell line/cell type Tumor cells and cell lines Tumor cells and cell lines Primary cells and co-cultures
Imaging clarity ++ +++ +++
Budget-friendly +++ ++ +
Cat. No. PK-6055330 (pack of 10)
PK-6055334 (case of 40)
PK-ISP-09-001 (pack of 10) PK-ISP-06-010 (pack of 3)
PK-ISP-06-001 (pack of 10)

 

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