Abl&Bcr-Abl Inhibitor |
Imatinib . mesylate |
Tyrosine kinase inhibitor(Highly specific for BCR-ABL) |
ALX-270-492 |
Abl&Bcr-Abl Inhibitor |
Dasatinib |
Potent tyrosine kinase inhibitor(Bcr-Abl, Src family, c-Kit) |
ab142050 |
Abl&Bcr-Abl Inhibitor |
GNF-2 |
Abl inhibitor |
Inquiry |
Abl&Bcr-Abl Inhibitor |
GNF-5 |
Abl inhibitor |
Inquiry |
ALK Inhibitor |
SB431542 |
ALK inhibitor |
ab120163 |
ALK Inhibitor |
NVP-TAE684 |
Highly potent, selective ALK inhibitor |
ab142082 |
ALK Inhibitor |
Crizotinib |
Potent c-MET and ALK inhibitor |
ENZ-CHM183 |
ALK Inhibitor |
Ceritinib (free base) |
Selective ALK inhibitor |
ENZ-CHM218 |
ALK Inhibitor |
AP26113 |
Pan inhibitor of ALK |
Inquiry |
ALK Inhibitor |
CH5424802 |
ALK inhibitor |
Inquiry |
ALK Inhibitor |
Doramapimod |
JNK, ALK, p38 MAPK inhibitor |
Inquiry |
ALK Inhibitor |
TAE684 |
ALK, c-Fes, LRRK2 inhibitor |
Inquiry |
AMPK Inhibitor |
BML-275 |
AMPK inhibitor |
BML-EI369 |
CDKs Inhibitor |
Purvalanol A |
Potent CDK inhibitor |
ab120304 |
CDKs Inhibitor |
Kenpaullone |
CDK2, GSK3β and LCK inhibitor |
ab120937 |
CDKs Inhibitor |
Indirubin |
Potent CDK and GSK3β inhibitor |
ab120960 |
CDKs Inhibitor |
Olomoucine II |
CDK/cyclin inhibitor |
ab141238 |
CDKs Inhibitor |
Aminopurvalanol A |
Cell permeable, reversible and competitive inhibitor of CDK/cyclin |
ALX-270-249 |
CDKs Inhibitor |
Alsterpaullone |
Inhibitor of CDK and GSK |
ALX-270-275 |
CDKs Inhibitor |
Indirubin-5-sulfonic acid . sodium salt |
Inhibitor of CDK and GSK |
ALX-270-296 |
CDKs Inhibitor |
5-Iodo-indirubin-3'-monoxime |
Inhibitor of GSK3β and CDK/cyclin |
ALX-270-424 |
CDKs Inhibitor |
RO-3306 |
Inhibitor of CDK1/cyclin B1 and CDK1/cyclin A |
ALX-270-463 |
CDKs Inhibitor |
UCN-01 |
PKC and CDK inhibitor |
ALX-380-222 |
CDKs Inhibitor |
Flavopiridol |
CDK inhibitor, interacts with multidrug resistance protein 1(MRP1) |
ALX-430-161 |
CDKs Inhibitor |
Indirubin-3'-monoxime |
Inhibitor of CDK and GSK3β |
BML-CC207 |
CDKs Inhibitor |
Abemaciclib |
CDK inhibitor |
Inquiry |
Chk1/2 Inhibitor |
CHIR-124 |
Novel and potent Chk1 inhibitor |
ab273615 |
Chk1/2 Inhibitor |
BML-277 |
Highly selective inhibitor of Chk2 |
BML-EI388 |
Chk1/2 Inhibitor |
LY2603618 |
Chk1 inhibitor |
Inquiry |
Chk1/2 Inhibitor |
LY2606368 |
Chk1 inhibitor |
Inquiry |
Chk1/2 Inhibitor |
SCH-900776 |
Chk1 inhibitor |
Inquiry |
c-MET Inhibitor |
SU 11274 |
Potent, selective cell-permeable Met inhibitor |
ab142159 |
c-MET Inhibitor |
Crizotinib |
Potent c-MET and ALK inhibitor |
ENZ-CHM183 |
c-MET Inhibitor |
Altiratinib |
c-MET, Tie-2, VEGFR inhibitor |
Inquiry |
c-MET Inhibitor |
AMG-208 |
c-MET and Ron inhibitor |
Inquiry |
c-MET Inhibitor |
AMG-458 |
c-MET inhibitor |
Inquiry |
c-MET Inhibitor |
INCB 28060 |
c-MET inhibitor |
Inquiry |
c-MET Inhibitor |
PF-04217903 |
c-MET inhibitor |
Inquiry |
CSF1R/Fms Inhibitor |
Pexidartinib |
Potent and selective MCSF Receptor inhibitor |
ab254454 |
CSF1R/Fms Inhibitor |
Sunitinib, Free base |
CSF-1 receptor kinase inhibitor |
ab285423 |
CSF1R/Fms Inhibitor |
PLX5622 (free base) |
Inhibitor of CSF1R |
ab287145 |
CSF1R/Fms Inhibitor |
BLZ-945 |
CSF-1R Inhibitor |
Inquiry |
EGFR/ErbB/HER Inhibitor |
Pelitinib (EKB-569) |
Irreversible EGFR inhibitor |
ab141171 |
EGFR/ErbB/HER Inhibitor |
Tyrphostin 25 (RG-50875) |
Competitive EGFR inhibitor |
ab141557 |
EGFR/ErbB/HER Inhibitor |
PD 174265 |
Potent, selective, reversible EGFR inhibitor |
ab145146 |
EGFR/ErbB/HER Inhibitor |
Lapatinib |
Cell-permeable, potent EGFR and HER2 inhibitor |
ab219408 |
EGFR/ErbB/HER Inhibitor |
Afatinib |
ErbB-1, -2 and -4 tyrosine kinase inhibitor |
ENZ-CHM158 |
EGFR/ErbB/HER Inhibitor |
AG 1478 |
EGFR inhibitor |
Inquiry |
EGFR/ErbB/HER Inhibitor |
AZD 9291 |
EGFR inhibitor |
Inquiry |
EGFR/ErbB/HER Inhibitor |
Gefitinib |
EGFR inhibitor |
Inquiry |
EGFR/ErbB/HER Inhibitor |
Neratinib |
EGFR inhibitor |
Inquiry |
EGFR/ErbB/HER Inhibitor |
WHI-P131 |
JAK3 and EGFR inhibitor |
Inquiry |
ERK Inhibitor |
Nimbolide |
CyclinA and ERK1/2 inhibitor |
ab142138 |
ERK Inhibitor |
Terrein |
Akt and ERK inhibitor |
ab144369 |
ERK Inhibitor |
Cafestol |
ERK2 and MEK1 inhibitor |
Inquiry |
ERK Inhibitor |
GDC-0994 |
ERK1/2 inhibitor |
Inquiry |
ERK Inhibitor |
LY-3214996 |
ERK1/2 inhibitor |
Inquiry |
ERK Inhibitor |
SCH 772984 |
ERK1/2 inhibitor |
Inquiry |
ERK Inhibitor |
VX-11e |
ERK2 inhibitor |
Inquiry |
FGFR Inhibitor |
PD 173074 |
Cell-permeable, potent inhibitor of FGF and VEGF receptors |
ENZ-CHM112 |
FGFR Inhibitor |
Infigratinib (free base) |
Pan FGFR kinase inhibitor |
ENZ-CHM225 |
FGFR Inhibitor |
AZD4547 |
FGFR inhibitor |
Inquiry |
FGFR Inhibitor |
BGJ398 |
FGFR inhibitor |
Inquiry |
FGFR Inhibitor |
LY-2874455 |
FGFR inhibitor |
Inquiry |
FLT3 Inhibitor |
TCS 359 |
Potent FLT3 inhibitor |
ab141268 |
FLT3 Inhibitor |
Crenolanib (CP-868596) |
Potent PDGFR and FLT3 inhibitor |
ab273385 |
FLT3 Inhibitor |
KW2449 |
Inhibits FLT3, ABL, and Aurora kinases |
ab273596 |
FLT3 Inhibitor |
Quizartinib |
Inhibitor of FLT3 and ABC(ATP-binding cassette) proteins |
ENZ-CHM154 |
FLT3 Inhibitor |
BMS-794833 |
MET, VEGFR2, Ron, Axl, FLT3 inhibitor |
Inquiry |
FLT3 Inhibitor |
Lestaurtinib |
PRK1, JAK, FLT3 inhibitor |
Inquiry |
FLT3 Inhibitor |
PKC412 |
PKC and FLT3 inhibitor |
Inquiry |
FLT3 Inhibitor |
Tandutinib |
FLT3, PDGFR, c-Kit inhibitor |
Inquiry |
GSK3 Inhibitor |
SB 216763 |
Potent, selective GSK3 inhibitor |
ab120202 |
GSK3 Inhibitor |
Kenpaullone |
CDK2, GSK3β and LCK inhibitor |
ab120937 |
GSK3 Inhibitor |
Indirubin |
Potent CDK and GSK3β inhibitor |
ab120960 |
GSK3 Inhibitor |
SB 415286 |
Potent, selective GSK3 inhibitor |
ab120962 |
GSK3 Inhibitor |
AR-A014418 |
Highly selective GSK-3 inhibitor |
ab141295 |
GSK3 Inhibitor |
CHIR 98014 |
Potent, selective ATP-competitive GSK3 inhibitor |
ab146582 |
GSK3 Inhibitor |
Alsterpaullone |
Inhibitor of CDK and GSK |
ALX-270-275 |
GSK3 Inhibitor |
Indirubin-5-sulfonic acid . sodium salt |
Inhibitor of CDK and GSK |
ALX-270-296 |
GSK3 Inhibitor |
2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole |
GSK-3β inhibitor |
ALX-270-358 |
GSK3 Inhibitor |
5-Iodo-indirubin-3'-monoxime |
Inhibitor of GSK3β and CDK/cyclin |
ALX-270-424 |
GSK3 Inhibitor |
1-Azakenpaullone |
GSK-3β inhibitor |
ALX-270-430 |
GSK3 Inhibitor |
Manzamine A |
GSK3 Inhibitor |
ALX-350-294 |
GSK3 Inhibitor |
6BIO |
Potent, reversible and ATP-competitive inhibitor of GSK3α/β |
ALX-430-156 |
GSK3 Inhibitor |
Indirubin-3'-monoxime |
Inhibitor of CDK and GSK3β |
BML-CC207 |
GSK3 Inhibitor |
SB-415286 |
GSK3β Inhibitor |
BML-EI311 |
GSK3 Inhibitor |
CHIR99021 |
GSK3 inhibitor |
Inquiry |
IGF-1R Inhibitor |
Picropodophyllotoxin |
Selective IGF-1R inhibitor |
ab144623 |
IGF-1R Inhibitor |
GSK1904529A |
Selective IGF-1R inhibitor |
ab273432 |
IGF-1R Inhibitor |
Tyrphostin AG 1024 |
Specific inhibitor of IGF-1 |
ALX-270-217 |
IGF-1R Inhibitor |
BMS 754807 |
InsR and IGF-1R inhibitor |
Inquiry |
IGF-1R Inhibitor |
Linsitinib |
IGF-1R and InsR inhibitor |
Inquiry |
IKKs Inhibitor |
SC-514 |
Selective, ATP-competitive, irreversible IKKβ inhibitor |
ab144415 |
IKKs Inhibitor |
CAY10575 |
IKK-ε inhibitor |
ab144424 |
IKKs Inhibitor |
BMS 345541 |
Highly selective cell permeable IKK-2 and IKK-1 inhibitor |
ab144822 |
IKKs Inhibitor |
IMD 0354 |
Potent, selective cell-permeable IKKβ inhibitor |
ab144823 |
IKKs Inhibitor |
IKK-16 |
Potent, selective IκB kinase inhibitor |
ab216471 |
IKKs Inhibitor |
BX795 |
Inhibitor of PDK1, TBK1, IKK-ε, IRF3 |
ENZ-CHM189 |
JAK Inhibitor |
Tofacitinib |
Potent, cell-permeable JAK inhibitor |
ab142068 |
JAK Inhibitor |
AG-490 |
Potent inhibitor of the JAK2 |
BML-EI272 |
JAK Inhibitor |
Ruxolitinib |
JAK inhibitor(JAK1 and JAK2) |
ENZ-CHM156 |
JAK Inhibitor |
Momelotinib |
Selective inhibitor of JAK1 and JAK2 kinases including the JAK2 V617F mutant |
ENZ-CHM197 |
JAK Inhibitor |
AZD-1480 |
JAK1/2 inhibitor |
Inquiry |
JAK Inhibitor |
Baricitinib |
Selective and reversible JAK inhibitor |
Inquiry |
JAK Inhibitor |
BMS-911543 |
JAK2 inhibitor |
Inquiry |
JAK Inhibitor |
CP 690,550 |
JAK1/2/3 inhibitor |
Inquiry |
JAK Inhibitor |
CYT-387 |
JAK2 inhibitor |
Inquiry |
JAK Inhibitor |
Filgotinib |
JAK1 inhibitor |
Inquiry |
JAK Inhibitor |
INCB018424 |
JAK1/2 inhibitor |
Inquiry |
JAK Inhibitor |
JAK2 Inhibitor V |
JAK2 inhibitor |
Inquiry |
JAK Inhibitor |
Lestaurtinib |
PRK1, JAK, FLT3 inhibitor |
Inquiry |
JAK Inhibitor |
TG101348 |
JAK2 inhibitor |
Inquiry |
JAK Inhibitor |
Tyrphostin AG 490 |
JAK2 inhibitor |
Inquiry |
JAK Inhibitor |
WHI-P131 |
JAK3 and EGFR inhibitor |
Inquiry |
JNK Inhibitor |
IQ-1S |
Selective JNK3 inhibitor |
ab146180 |
JNK Inhibitor |
SR 3576 |
Potent, selective JNK3 inhibitor |
ab146429 |
JNK Inhibitor |
DB07268 |
JNK1 inhibitor |
ab282444 |
JNK Inhibitor |
AS601245 |
Potent and cell permeable ATP competitive JNK inhibitor |
ALX-270-443 |
JNK Inhibitor |
SP600125 |
Potent, cell permeable, selective, and reversible inhibitor of JNK |
BML-EI305 |
JNK Inhibitor |
Doramapimod |
JNK, ALK, p38 MAPK inhibitor |
Inquiry |
MEK Inhibitor |
PD 184352 (CI-1040) |
Potent, highly selective ATP non-competitive MEK1/2 inhibitor |
ab141348 |
MEK Inhibitor |
Hypothemycin |
Potent, selective MEK inhibitor |
ab144277 |
MEK Inhibitor |
BIX 02188 |
Potent, selective MEK5 inhibitor |
ab144572 |
MEK Inhibitor |
AZD8330 |
A selective allosteric MEK inhibitor |
ab235504 |
MEK Inhibitor |
Pimasertib (AS-703026) |
Selective and potent ATP non-competitive allosteric inhibitor of MEK1/2 |
ab235569 |
MEK Inhibitor |
PD-98059 |
Potent and selective inhibitor of MEK |
BML-EI360 |
MEK Inhibitor |
SL-327 |
Selective inhibitor of MEK1 and MEK2 |
BML-EI365 |
MEK Inhibitor |
Selumetinib |
Potent and selective ATP non-competitive inhibitor of MEK1/2 |
ENZ-CHM184 |
MEK Inhibitor |
PD0325901 |
Selective MEK inhibitor |
ENZ-CHM202 |
MEK Inhibitor |
Trametinib |
Potent MEK1/2 inhibitor |
ENZ-CHM239 |
MEK Inhibitor |
Cafestol |
ERK2 and MEK1 inhibitor |
Inquiry |
MEK Inhibitor |
GDC-0623 |
MEK inhibitor |
Inquiry |
MEK Inhibitor |
TAK-733 |
MEK inhibitor |
Inquiry |
mTOR Inhibitor |
CAY10626 |
Potent PI3Kα/mTOR inhibitor |
ab120903 |
mTOR Inhibitor |
Everolimus |
Potent mTOR inhibitor |
ab142151 |
mTOR Inhibitor |
OSI-027 |
Potent mTOR inhibitor |
ab273522 |
mTOR Inhibitor |
PI-103 |
Inhibitor of DNA-PK, PI3 kinase and mTOR |
ALX-270-460 |
mTOR Inhibitor |
pp242 . hydrate |
Inhibitor of both mTORC1 and mTORC2 |
ENZ-CHM132 |
mTOR Inhibitor |
mTOR inhibitor WYE-23 |
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor |
ENZ-CHM136 |
mTOR Inhibitor |
mTOR inhibitor WYE-28 |
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor |
ENZ-CHM137 |
mTOR Inhibitor |
AZD8055 |
A potent mTOR inhibitor |
ENZ-CHM193 |
mTOR Inhibitor |
AZD-2014 |
mTOR inhibitor |
Inquiry |
mTOR Inhibitor |
BEZ235 |
PI3K and mTOR inhibitor |
Inquiry |
mTOR Inhibitor |
Ciclopirox Olamine |
mTOR inhibitor |
Inquiry |
mTOR Inhibitor |
Torin 1 |
mTORC1/2 inhibitor |
Inquiry |
mTOR Inhibitor |
Torin 2 |
mTORC1/2 inhibitor |
Inquiry |
P13K Inhibitor |
CAY10626 |
Potent PI3Kα/mTOR inhibitor |
ab120903 |
P13K Inhibitor |
ZSTK474 |
Inhibits all four PI3K isoforms |
ALX-270-454 |
P13K Inhibitor |
Compound 15e |
PI3 kinase inhibitor |
ALX-270-455 |
P13K Inhibitor |
PI-103 |
Inhibitor of DNA-PK, PI3 kinase and mTOR |
ALX-270-460 |
P13K Inhibitor |
AS-604850 |
PI3 kinase p110γ inhibitor |
ALX-270-461 |
P13K Inhibitor |
AS-605240 |
PI3 kinase p110γ inhibitor |
ALX-270-462 |
P13K Inhibitor |
TGX-221 |
PI3 kinase p110β inhibitor |
ALX-270-464 |
P13K Inhibitor |
AS-252424 |
PI3 kinase p110γ inhibitor |
ALX-270-465 |
P13K Inhibitor |
Wortmannin |
PI3 kinase inhibitor |
BML-ST415 |
P13K Inhibitor |
LY 294002 |
PI3 kinase inhibitor |
BML-ST420 |
P13K Inhibitor |
GDC-0941 |
Cell-permeable, potent inhibitor of PI3 kinase IA and IB |
ENZ-CHM130 |
P13K Inhibitor |
Alpelisib (free base) |
Potent and selective PI3Kα inhibitor |
ENZ-CHM214 |
P13K Inhibitor |
Duvelisib (free base) |
Highly selective inhibitor of PI3K-δ and PI3K-γ |
ENZ-CHM223 |
P13K Inhibitor |
Idelalisib (free base) |
I3K-δ inhibitor |
ENZ-CHM224-0025 |
P13K Inhibitor |
BEZ235 |
PI3K and mTOR inhibitor |
Inquiry |
P13K Inhibitor |
GDC-0032 |
PI3K inhibitor |
Inquiry |
P13K Inhibitor |
GSK2334470 |
PI3K and PDK1 inhibitor |
Inquiry |
p38 MAPK Inhibitor |
SB 203580 |
p38 MAPK inhibitor |
ab120162 |
p38 MAPK Inhibitor |
TAK 715 |
Potent p38 MAPK inhibitor |
ab120989 |
p38 MAPK Inhibitor |
LY 2228820 |
A novel and potent inhibitor of p38 MAPK |
ab143833 |
p38 MAPK Inhibitor |
p38 MAP Kinase Inhibitor |
Potent p38 MAPK inhibitor |
ab145872 |
p38 MAPK Inhibitor |
VX-745 |
Potent, selective p38 alpha MAPK inhibitor |
ab230367 |
p38 MAPK Inhibitor |
SB239063 |
Potent, cell permeable inhibitor of p38 MAPK |
ALX-270-351 |
p38 MAPK Inhibitor |
SB-202190 |
Cell permeable, potent and selective p38 MAPK (p38α and ß) |
BML-EI294 |
p38 MAPK Inhibitor |
SD-169 |
Selective inhibitor of p38α |
BML-EI371 |
p38 MAPK Inhibitor |
Doramapimod |
JNK, ALK, p38 MAPK inhibitor |
Inquiry |
PDPK1/PDK1 Inhibitor |
BX-795 |
Inhibitor of PDK1, TBK1, IKK-ε, IRF3 |
ENZ-CHM189 |
PDPK1/PDK1 Inhibitor |
GSK2334470 |
PI3K and PDK1 inhibitor |
Inquiry |
PDPK1/PDK1 Inhibitor |
KT5720 |
PKA and PDK1 inhibitor |
Inquiry |
PDPK1/PDK1 Inhibitor |
PHT-427 |
PDK1 and Akt inhibitor |
Inquiry |
PKB/Akt Inhibitor |
SC-66 |
Allosteric Akt inhibitor |
ab120802 |
PKB/Akt Inhibitor |
Triciribine |
Selective, potent inhibitor of Akt activation |
ab120936 |
PKB/Akt Inhibitor |
(-)-Deguelin |
Akt inhibitor |
ab120941 |
PKB/Akt Inhibitor |
Isobavachalcone |
Akt inhibitor |
ab141168 |
PKB/Akt Inhibitor |
Perifosine |
Akt inhibitor |
ab142055 |
PKB/Akt Inhibitor |
Akt Inhibitor (Akti-1/2) |
Potent isozyme selective Akt1/2 kinase inhibitor |
ab142088 |
PKB/Akt Inhibitor |
3-BrB-PP1 |
Akt inhibitor |
ab143756 |
PKB/Akt Inhibitor |
Terrein |
Akt and ERK inhibitor |
ab144369 |
PKB/Akt Inhibitor |
Miransertib |
Allosteric, selective, non-ATP competitive pan-Akt inhibitor |
ab235550 |
PKB/Akt Inhibitor |
CCT128930 |
Potent and selective AKT2 inhibitor |
ab273533 |
PKB/Akt Inhibitor |
Ipatasertib (GDC-0068) |
Selective Akt1/2/3 inhibitor |
ab273621 |
PKB/Akt Inhibitor |
A-674563 |
Potent and selective AKT1 inhibitor |
ab282439 |
PKB/Akt Inhibitor |
AT 7867 |
Akt1/2/3 and p70S6K/PKA inhibitor |
ab282448 |
PKB/Akt Inhibitor |
SH-5 |
Akt inhibitor |
ALX-270-349 |
PKB/Akt Inhibitor |
ML-9 |
PKB inhibitor |
BML-EI153 |
PKB/Akt Inhibitor |
BML-257 |
Akt inhibitor |
BML-EI336 |
PKB/Akt Inhibitor |
Akt Inhibitor VIII |
Potent inhibitor of Akt1, Akt2 and Akt3 |
ENZ-CHM125 |
PKB/Akt Inhibitor |
10-DEBC . hydrochloride |
Selective inhibitor of Akt (PKB) |
ENZ-CHM126 |
PKB/Akt Inhibitor |
MK-2206 . 2HCl |
Highly selective inhibitor of Akt1, Akt2 and Akt3 |
ENZ-CHM164 |
PKB/Akt Inhibitor |
AZD 5363 |
Akt inhibitor |
Inquiry |
PKB/Akt Inhibitor |
PHT-427 |
PDK1 and Akt inhibitor |
Inquiry |
PLKs Inhibitor |
(R)-BI-2536 |
Potent and selective inhibitor of mammalian Plk1 |
ENZ-CHM160 |
PLKs Inhibitor |
BI-6727 |
PLK1 inhibitor |
Inquiry |
PLKs Inhibitor |
GSK461364 |
PLK1 inhibitor |
Inquiry |
PLKs Inhibitor |
NMS-1286937 |
PLK1 inhibitor |
Inquiry |